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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1930
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Mice were dosed with up to 1000 mg/kg with the Target Substance and all survived. Although this study is not a guideline study, there is sufficient weight of evidence to conclude that the material is of low acute oral toxicity.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1930

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
please refer to the executive summary
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methoxybutyl acetate
EC Number:
224-644-9
EC Name:
3-methoxybutyl acetate
Cas Number:
4435-53-4
Molecular formula:
C7H14O3
IUPAC Name:
3-methoxybutyl acetate
Constituent 2
Reference substance name:
Butoxyl
IUPAC Name:
Butoxyl

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
100 mg/kg bw
500 mg/kg bw
1000 mg/kg bw
6 x once /day 100mg/kg
No. of animals per sex per dose:
two per dose
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 1 000 mg/kg bw
Mortality:
No mortality observed
Other findings:
Animals remained healthy

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
After oral application of up 1000 mg/kg bw, no mortality occured.
Executive summary:

Test material was administered as single dose at levels: 100 mg/kg bw; 500 mg/kg bw and 1000 mg/kg bw. No effects were observed at the treatment doses.

LD 50 > 1000 mg/kg bw.