Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

A radiolabelled study of the metabolism of DEGDB in the rat by oral gavage demonstrated that DEGDB does not have a tendency to bioaccumulate.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

In a metabolism study conducted to OECD guideline 417, virtually all of single oral doses of 50 and 750 mg/kg of [ring-U-14C-phenyl] DEGDB administered to Sprague-Dawley CD rats were absorbed metabolised and excreted in the urine within 24 hours of administration. DEGDB was metabolised via hydrolysis of the ester bonds to benzoic acid; this free acid was then conjugated with either glycine (major pathway) or glucuronic acid (minor pathway) prior to excretion.