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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
96 hour acute
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data taken from a review of nitro-phenol.
4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects.

Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified
Specific details on test material used for the study:
No specific details on purity
4-Nitrophenol considered suitable for read-across potential for biodegradation as the oxidation form of the nitrogen is not critical for degradation characteristics.
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Details on test organisms:
Data on two species are provided; this proved the more sensitive species
Test type:
static
Water media type:
freshwater
Total exposure duration:
96 h
Hardness:
Not specified
Test temperature:
Not specified
pH:
Not specified
Dissolved oxygen:
Not specified
Reference substance (positive control):
not specified
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 3.8 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
A flow-through study is also cited, with LC50 reported 7.93 mg/l
The lower figure from the static test is used for this assessment.
Validity criteria fulfilled:
not specified
Executive summary:

A flow-through study is also cited, with LC50 reported 7.93 mg/l

The lower figure from the static test is used for this assessment.

The substance need not be classified based on this result in view of ready-biodegradation

4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects.

Description of key information

A flow-through study is also cited, with LC50 reported 7.93 mg/l

The lower figure from the static test is used for this assessment.

The substance need not be classified based on this result in view of ready-biodegradation

4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
3.8 mg/L

Additional information