Registration Dossier
Registration Dossier
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EC number: 206-746-5 | CAS number: 372-18-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 1,3-difluorobenzene
- EC Number:
- 206-746-5
- EC Name:
- 1,3-difluorobenzene
- Cas Number:
- 372-18-9
- Molecular formula:
- C6H4F2
- IUPAC Name:
- 1,3-difluorobenzene
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.52
- Temp.:
- 25 °C
- pH:
- 6.5
Any other information on results incl. tables
No. |
standards |
logPow |
Retention time /min |
Average value of retention time/min |
capacity factor k |
logk |
1 |
Formamide |
/ |
2.133 |
2.133 |
0 |
/ |
|
|
|
|
|
|
2.133 |
2 |
Acetanilide |
1.0 |
2.619 |
2.619 |
0.2278 |
-0.6424 |
|
|
|
|
|
|
2.619 |
3 |
Phenol |
1.5 |
2.823 |
2.825 |
0.3242 |
-0.4892 |
|
|
|
|
|
|
2.826 |
4 |
2-Nitrophenol |
1.8 |
3.596 |
3.596 |
0.6859 |
-0.1637 |
|
|
|
|
|
|
3.596 |
5 |
Anisole |
2.1 |
4.486 |
4.486 |
1.1031 |
0.0426 |
|
|
|
|
|
|
4.486 |
6 |
Toluene |
2.7 |
6.283 |
6.283 |
1.9456 |
0.2891 |
|
|
|
|
|
|
6.283 |
7 |
Bromobenzene |
3.0 |
6.673 |
6.671 |
2.1275 |
0.3279 |
|
|
|
|
|
|
6.669 |
8 |
Naphthalene |
3.6 |
7.463 |
7.461 |
2.4979 |
0.3976 |
|
|
|
|
|
|
7.459 |
Injection |
Retention time/min |
capacity factor k |
log k |
log Pow |
Average value |
1 |
4.809 |
1.2546 |
0.0985 |
2.52 |
2.5 |
|
2 |
4.809 |
1.2546 |
0.0985 |
2.52 |
Applicant's summary and conclusion
- Conclusions:
- log Pow = 2.5
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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