Registration Dossier
Registration Dossier
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EC number: 203-483-8 | CAS number: 107-35-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- ECOSAR Version 1.11
QMRF for this informatic tool is not available. However, this informatic tool is widely used and reported in ECHA Practical Guide - How to use and report (Q)SARs, Version 3.1 (July 2016).
The ecological structure activity relationships (ECOSAR) class program is a collection of QSAR models estimating aquatic toxicity, including short-term toxicity to fish. Most of the ECOSAR models are based on the relationships between log Kow and toxicity (LC50 or EC50) and take into account different structural classes.
Data source
Reference
- Reference Type:
- other:
- Title:
- ECOSAR (US EPA)
- Year:
- 2 018
- Bibliographic source:
- ECOSAR (US EPA) Version 1.11
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The ecological structure activity relationships (ECOSAR) class program is a collection of QSAR models estimating aquatic toxicity, including short-term toxicity to fish. Most of the ECOSAR models are based on the relationships between log Kow and toxicity (LC50 or EC50) and take into account different structural classes.
Test material
- Reference substance name:
- Taurine
- EC Number:
- 203-483-8
- EC Name:
- Taurine
- Cas Number:
- 107-35-7
- Molecular formula:
- C2H7NO3S
- IUPAC Name:
- 2-aminoethanesulfonic acid
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- The substance to be evaluated is: Taurine - IUPAC name: 2-aminoethanesulfonic acid
C(CS(=O)(=O)O)N
Test organisms
- Test organisms (species):
- other: Green Algae
Results and discussion
Effect concentrations
- Remarks on result:
- not measured/tested
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Aliphatic Amines : Green Algae 96-hr EC50 1.45e+005 mg/L*
Aliphatic Amines : Green Algae ChV 30695.793 mg/L
Neutral Organic SAR: Green Algae 96-hr EC50 2.24e+005 mg/L*
Neutral Organic SAR: Green Algae ChV 19449.820 mg/L
* Chemical may not be soluble enough to measure this predicted effect. If the effect level exceeds the water solubility by 10X, typically no effects at saturation (NES) are reported.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
