Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 213-485-0 | CAS number: 957-68-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 24, 2012 to October 26, 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study (OECD109) with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 610.7 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 5 g/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- >= 3.7 - <= 3.8
- Details on results:
- Mean water solubility: 610.7 mg/L at 20 °C. Standard deviation: 19.4 mg/L.
- Conclusions:
- Mean water solubility is 610.7 mg/L at 20 °C.
- Executive summary:
The water solubility at 20 °C of test item was determined by the flask method, according to OECD Test Guideline 105 and EC No. 440/2008 Part A. Method A.6.
The mean water solubility is 610.7 mg/L at 20 °C.
Reference
For the main test three flasks were prepared with an amount of test item and water, and one flask only with water. After stirring and centrifugation the aqueous phases were measured by means of HPLC. The solution of each flask has been measured twice. The results of these measurements are shown inTable4. The values represented in the table are rounded values. The calculation was carried out with the original not rounded values.
Table4: Results of the flask method
flask |
1a |
2a |
3a |
4a |
measured value [mg/L] |
6.16 / 6.11 |
6.30 / 6.28 |
5.91 / 5.90 |
0 / 0 |
aliquot of the flask [mL] |
0.5 |
0.5 |
0.5 |
0.5 |
total volume after the 1stdilution [mL] |
25 |
25 |
25 |
25 |
aliquot of the 1stdilution [mL] |
1 |
1 |
1 |
1 |
total volume after the 2nddilution [mL] |
2 |
2 |
2 |
2 |
water solubility [mg/L] |
615.8 / 610.5 |
629.9 / 627.6 |
590.6 / 589.6 |
0 / 0 |
average water solubility [mg/L] |
613.2 |
628.7 |
590.1 |
0 |
mean value of the water solubility [mg/L] |
610.7 |
|||
standard deviation [mg/L] |
19.4 |
|||
relative standard deviation [%] |
3.2 |
|||
Description of key information
The mean water solubility is 610.7 mg/L at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 610.7 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
