Registration Dossier
Registration Dossier
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EC number: 208-589-8 | CAS number: 534-15-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental start date 13 December 2017 Experimental completion date 08 March 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Deviations:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Identity: 1,1-Dimethoxyethane
CAS number: 534-15-6
Batch number: 1710091650R
Purity: 99.91%
Physical state / Appearance: Clear liquid
Expiry date: 09 October 2019
Storage conditions: Refrigerator (2 - 8°C), under nitrogen, in the dark
Date received: 30 October 2017 - Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 0.63
- Temp.:
- 25 °C
- pH:
- 7
- Conclusions:
- The test item, 1,1-Dimethoxyethane, was found to have a log10Pow value of 0.63.
- Executive summary:
The test item, 1,1-Dimethoxyethane, was found to have a log10Pow value of 0.63 using a procedure designed to be compatible with EC Method A.8 and OECD Method 117
Reference
HPLC Determination of Log10Pow for 1,1-Dimethoxyethane
Sample |
Component |
tr(minutes) |
k' |
log10k’ |
log10Pow |
Standard Run A |
Acetanilide |
1.788 |
0.247 |
-0.608 |
1.00 |
(t0= 1.434 minutes) |
Nitrobenzene |
2.348 |
0.637 |
-0.196 |
1.90 |
|
Ethylbenzoate |
3.389 |
1.363 |
0.135 |
2.60 |
|
Bromobenzene |
4.479 |
2.123 |
0.327 |
3.00 |
|
Benzylbenzoate |
6.096 |
3.251 |
0.512 |
4.00 |
|
DDT |
35.528 |
23.775 |
1.376 |
6.20 |
Sample A |
1,1-Dimethoxyethane |
1.684 |
0.212 |
-0.675 |
0.63 |
(t0= 1.390 minutes) Sample B |
1,1-Dimethoxyethane |
1.685 |
0.214 |
-0.670 |
0.64 |
(t0= 1.388 minutes) Standard Run B |
Acetanilide |
1.785 |
0.247 |
-0.607 |
1.00 |
(t0= 1.431 minutes) |
Nitrobenzene |
2.346 |
0.639 |
-0.194 |
1.90 |
|
Ethylbenzoate |
3.388 |
1.368 |
0.136 |
2.60 |
|
Bromobenzene |
4.480 |
2.131 |
0.329 |
3.00 |
|
Benzylbenzoate |
6.102 |
3.264 |
0.514 |
4.00 |
|
DDT |
35.626 |
23.896 |
1.378 |
6.20 |
Linear regression (based on mean of standard runs A and B): log10Pow = 2.67log10k’ + 2.43
Description of key information
The test item, 1,1-Dimethoxyethane, was found to have a log10Pow value of 0.63 using a procedure designed to be compatible with EC Method A.8 and OECD Method 117
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.63
- at the temperature of:
- 25 °C
Additional information
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