1,3-bis(hydroxymethyl)urea

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2011-09-27 to 2001-11-02

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Key result

Temp.:

20 °C

Vapour pressure:

< 0 hPa

Temp.:

25 °C

Vapour pressure:

< 0 hPa

Temp.:

50 °C

Vapour pressure:

< 0 hPa

The regression of the vapour pressure data leads with a mean deviation of 13 % to the following function:

ln (p/hPa) = 32.1887 - 15770.76 / (T/K)

Using this function, the vapour pressure of the test substance for 20, 25 and 50 °C were extrapolated.

In the temperature range used for vapour pressure measurements the test item was solid.

Table 1. Measured vapour pressures of the test substance

Temperature	Vapour pressure, p/hPa
t/°C	Cell 2	Cell 3
68.3	9.98·10^-7	1.02·10^-6
78.1	2.56·10^-6	2.43·10^-6
97.5	3.33·10^-5	3.44·10^-5

Conclusions:

The vapour pressure of the test substance at 20 °C and 25 °C was extrapolated using a regression function to be the same: < 1.0E-6 hPa.

Executive summary:

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item. The vapour pressure of the test item was determined at three different temperatures (68, 78 and 97 °C) using the effusion method (weight loss). All measured values showed good reproducibility, giving relative standard deviations of less than 25 %, and perfect correlation. Therefore, the result of the test according to the guideline criteria was considered to be valid. The vapour pressure was calculated using the linear regression equation of the Ln P versus 1/T function. The vapour pressure was calculated to be < 1.0E-6 hPa at 20 °C and 25 °C.

Description of key information

The vapour pressure of the test substance at 20 °C and 25 °C was extrapolated using a regression function to be the same: < 1.0E-6 hPa.

Additional information

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item (reference 4.6-1). The vapour pressure of the test item was determined at three different temperatures (68, 78 and 97 °C) using the effusion method (weight loss). All measured values showed good reproducibility, giving relative standard deviations of less than 25 %, and perfect correlation. Therefore, the result of the test according to the guideline criteria was considered to be valid. The vapour pressure was calculated using the linear regression equation of the Ln P versus 1/T function. The vapour pressure was calculated to be < 1.0E-6 hPa at 20 °C and 25 °C.