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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The EC50(48h) = ca. 316 mg/L for Daphnia magna (OECD 202)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
316 mg/L

Additional information

There is one short-term aquatic invertebrate study available for 2-amino-2-methyl-1,3-propanediol (AMPD), which was used as key study for the assessment. The study was conducted according the OECD guideline 202 and GLP (M B Claude, 2010). The test organism Daphnia magna was exposed to AMPD in a static system for 48 hours, at the measured test concentrations 0.1, 1.0, 10, 100 1000 mg./L. At 100 mg/l, all the daphnids appeared to have normal mobility and at 1000 mg/l, 8 to 9 out of 10 daphnids appeared lethargic. The EC50 value was therefore estimated to be 316 mg/L using Binomial Probability.