Registration Dossier
Registration Dossier
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EC number: 201-849-1 | CAS number: 88-66-4
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Principles of method if other than guideline:
- DIN 38412 Part 11
Test material
- Reference substance name:
- 1-chloro-2-(dichloromethyl)benzene
- EC Number:
- 201-849-1
- EC Name:
- 1-chloro-2-(dichloromethyl)benzene
- Cas Number:
- 88-66-4
- Molecular formula:
- C7H5Cl3
- IUPAC Name:
- 1-chloro-2-(dichloromethyl)benzene
- Details on test material:
- Analytical purity: >99%
Constituent 1
Test solutions
- Details on test solutions:
- - Stock solution: saturated solution prepared by stirring a batch in water at room temperature for 72h and filtrating it through a folded paper filter;
- Concentration of stock solution: 336 mg DOC/L, correspoinding to 781 mg/l 2-Chlorobenzal chloride;
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
Test conditions
- Test temperature:
- Roomtemperature
- Nominal and measured concentrations:
- Nominal concentrations: Dilution of the stock solution with 336 mg DOC/L, corresponding to 781 mg/l 2-Chlorobenzal chloride
Diluted from 1:100 corresponding to 7.81 mg/l test substance up to 1:1 nominal concetration.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 78.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 437 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 782 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Confidence interval of EC50: 361.0 mg/L - 529.6 mg/L
Applicant's summary and conclusion
- Conclusions:
- With the indicated test data the EC50 of 2-Chlorobenzalchloride to Daphnia magna under the conditions of the test was estimated to be ca. 400 mg/l.
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