Registration Dossier
Registration Dossier
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EC number: 206-746-5 | CAS number: 372-18-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- Publication in Russian
Data source
Reference
- Reference Type:
- publication
- Title:
- 1,3-DFB: No information
- Author:
- No information
- Year:
- 1 965
- Bibliographic source:
- Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. Vol. 3, Pg. 91
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,3-difluorobenzene
- EC Number:
- 206-746-5
- EC Name:
- 1,3-difluorobenzene
- Cas Number:
- 372-18-9
- Molecular formula:
- C6H4F2
- IUPAC Name:
- 1,3-difluorobenzene
- Test material form:
- liquid
- Details on test material:
- Name of the test material: 1,3-difluorobenzene
No data available
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- inhalation
- Duration of exposure:
- 2 h
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LC50
- Effect level:
- 55 mg/L air
- Exp. duration:
- 2 h
- Dose descriptor:
- LC50
- Effect level:
- 43.65 mg/L air
- Exp. duration:
- 4 h
- Remarks on result:
- other: calculated with Haber's law
- Clinical signs:
- other: Brain and coverings: recordings from specific areas of central nervous system
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute inhalation LC50 - 2h value of 1,3-difluorobenzene was found to be 55 mg/L in mouse. The LC50 - 4h calculated with Haber's law was found to be 43.65 mg/L.
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