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Toxicological information

Endpoint summary

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Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Several Ames tests and a data from a SOS Chromotest and a QSAR ccaluculation are available

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (positive)

Additional information

Additional information from genetic toxicity in vitro:

In the Ames tests, the SOS Chromotest and the QSAR calculation 1,8-naphthylenediamine are positive

Justification for selection of genetic toxicity endpoint
key study used

Justification for classification or non-classification

The compound is positive in bacterial reverse mutation assays. No other studies are available.