Registration Dossier
Registration Dossier
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EC number: 203-915-5 | CAS number: 111-85-3
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
No significant bioaccumulation of n-Octylchlorid is expected (reported BCF values for the read-across substance 1,8-dichlorooctan from 148 to 692 with Cyprinus carpio, tested in concentrations of 10 and 100 µg/L).
Key value for chemical safety assessment
- BCF (aquatic species):
- 692 dimensionless
Additional information
There is no experimental data available regarding bioaccumulation of n-Octyl chlorid in fish.
For 1,8-dichlorooctan (CAS 2162-99-4) a study in accordance with OECD 305 C (flow-through study over 8 weeks, 2 concentrations tested, test design improved for a volatile substance) is available.
1,8-dichlorooctane is structurally very similar to n-Octyl chlorid and has even a higher calculated logKow value (4.78 calculated with KOWWIN v1.68) than n-Octyl chlorid (4.52 calculated with KOWWIN v1.68). In contrast to n-Octyl chlorid, 1,8-dichlorooctane is not readily biodegradable according to the disseminated REACH dossier at the ECHA website. Therefore, using bioaccumulation data from 1,8-dichlorooctane for predicting the bioaccumulation potential of n-Octyl chlorid can be regarded as a worst case approach.
With BCFs of 148-409 for the 0.01mg/L concentration and 281-692 for the 0.1 mg/L concentration, the study clearly indicates that 1,8-dichlorooctan and therefore also n-Octyl chlorid does not fulfill the B criterion (BCF <2000).
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