Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
8 December 2008 - 23 January 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted to GLP in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
isoteniscope

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid (not specified)
Details on test material:
Description: dark brown liquid
Storage conditions: room temperature, in the dark

Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
4 900 Pa

Any other information on results incl. tables

Run 1

A plot of Log (vapour pressure (Pa)) versus reciprocal temperature (1 / T (K)) gives the following statistical data using an unweighted least squares treatment:

Slope: -1890.218

Standard deviation in slope: 16.170

Intercept: 10.014

Standard deviation in intercept: 0.048

The results indicate the following relationship: Log (Vp (Pa)) = -1890.218 / temp (K) + 10.014

This yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 3.674.

 

Run 2

A plot of Log (vapour pressure (Pa)) versus reciprocal temperature (1 / T (K)) gives the following statistical data using an unweighted least squares treatment:

Slope: -1813.476

Standard deviation in slope: 8.828

Intercept: 9.806

Standard deviation in intercept: 0.026

The results indicate the following relationship: Log (Vp (Pa)) = -1813.476 / temp (K) + 9.806

This yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 3.273.

 

Run 3

A plot of Log (vapour pressure (Pa)) versus reciprocal temperature (1 / T (K)) gives the following statistical data using an unweighted least squares treatment:

Slope: -2088.029

Standard deviation in slope: 15.617

Intercept: 10.554

Standard deviation in intercept: 0.046

The results indicate the following relationship: Log (Vp (Pa)) = -2088.029 / temp (K) + 10.554

This yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 3.551.

 

Run 4

A plot of Log (vapour pressure (Pa)) versus reciprocal temperature (1 / T (K)) gives the following statistical data using an unweighted least squares treatment:

Slope: -1582.976

Standard deviation in slope: 8.271

Intercept: 9.170

Standard deviation in intercept: 0.024

The results indicate the following relationship: Log (Vp (Pa)) = -1582.976 / temp (K) + 9.170

This yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 3.861.

 

Run 5

A plot of Log (vapour pressure (Pa)) versus reciprocal temperature (1 / T (K)) gives the following statistical data using an unweighted least squares treatment:

Slope: -1913.444

Standard deviation in slope: 7.477

Intercept: 10.059

Standard deviation in intercept: 0.022

The results indicate the following relationship: Log (Vp (Pa)) = -1913.444 / temp (K) + 10.059

This yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 3.641.

 

Table 1 Summary of Results

Run

Log [Vp (25 °C)]

1

3.674

2

3.723

3

3.551

4

3.861

5

3.641

Mean = 3.690

Vapour Pressure = 4.9 x 10³ Pa

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the test material has been determined to be 4.9 x 10³ Pa at 25 °C.
Executive summary:

The vapour pressure of the test material was investigated in accordance with the standardised guideline EU Method A.4 using an isoteniscope system with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25 °C.

The vapour pressure of the test material has been determined to be 4.9 x 10³ Pa at 25 °C.