Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
5 December 2008 - 17 February 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted to GLP in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
other: BS4633: Method for the Determination of Crystallizing Point
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
method to determine freezing temperature

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid (not specified)
Details on test material:
Description: dark brown liquid
Storage conditions: room temperature, in the dark

Results and discussion

Melting / freezing point
Melting / freezing pt.:
270 K
Remarks on result:
other: The test material only partially solidified to a 'slush-like' consistency. The temperature was within ± 0.5 K.

Any other information on results incl. tables

Table 1 Cooling data for Determination 1

Time (s)

Temperature (K)

Time (s)

Temperature (K)

0

292

540

274

30

292

570

273

60

291

600

272

90

289

630

271

120

288

660

270

150

287

690

270

180

286

720

270

210

285

750

269

240

284

780

269

270

283

810

268

300

282

840

268

330

280

870

270

360

280

900

270

390

278

930

270

420

278

960

270

450

277

990

270

480

276

1020

270

510

275

 

 

 

Table 2 Cooling data for Determination 2

Time (s)

Temperature (K)

Time (s)

Temperature (K)

0

294

510

273

30

293

540

272

60

292

570

271

90

290

600

271

120

288

630

270

150

287

660

269

180

286

690

268

210

285

720

270

240

284

750

270

270

283

780

270

300

282

810

270

330

280

840

270

360

279

870

270

390

278

900

270

420

276

930

270

450

275

960

270

480

274

 

 

Applicant's summary and conclusion

Conclusions:
The freezing temperature of the test material was determined to be 270 ± 0.5 K. However, it only partially solidified to a "slush-like" consistency.
Executive summary:

The freezing temperature of the test material was investigated and the determination was carried out in accordance with the standardised guidelines EU Method A.1 and BS4633: Method for the Determination of Crystallizing Point.

The freezing temperature of the test material was determined to be 270 ± 0.5 K. However, it only partially solidified to a "slush-like" consistency.