Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs.

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

in between 2010/03/09 - 2010/05/07

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

yes

Remarks:

Preliminary test was not performed according to guideline

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Water solubility:

80.8 mg/L

Temp.:

20 °C

pH:

> 6.9 - < 7.2

Remarks on result:

other: 20 °C ± 0.5 °C

The preliminary estimate of water solubility was approximately 8.0 x 10^-2 g/L. The results from the definitive study are shown in Table 3.

Table 3: Results from the definitive study

Sample No.	Time Shaken at ~ 30 °C [h]	Time Equilibrated at 20 °C [h]	Concentration [g/L]	Solution pH
1	72	24	7.74 x 10^-2	6.9
2	48	24	8.05 x 10^-2	7.0
3	24	24	8.42 x 10^-2	7.2

Testing was also carried out using a loading rate of approximately 0.10 g test item plus 100 mL glass double-distilled water. However, at this much higher loading rate, the samples could not be cleaned-up fully. Consequently, as the preliminary and definitive test samples were all noted to contain undissolved test item prior to clean-up, the results and conclusion are considered to be valid.

The spectrophotometric analytical methodology used was based on a method supplied by the Sponsor.

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)

Description of key information

80.8 mg/L at 20 °C ± 0.5 °C, pH 6.9-7.2 (Walker, J.A., Croda Europe Ltd., 2010)

Key value for chemical safety assessment

Water solubility:

80.8 mg/L

at the temperature of:

20 °C