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EC number: 807-040-5
CAS number: 4538-42-5
Acute toxicity to fish: The
96h-LC0 for 1,6 -diisocyanatohexane (CAS 822 -06 -0) was found to be >=
82.8 mg/L and the result is related to the arithmetic mean of analytical
values (Caspers, 2000). The result relates to 1,6 -diisocyanatohexane
(CAS 822 -06 -0) which was used in a read-across approach. 1,6
Diisocyanatohexane is a similar substance as Pentane, 1,5 -diisocyanato-
containing an alkyl chain of 6 C-atoms, whereas Pentane, 1,5
–diisocyanato contains 5 C-atoms.
Acute toxicity to daphnia: After
48 hrs no toxic effects against daphnia magna were observed at the limit
loading of 100 mg/L under exposure conditions (Spoo-Klöppel, 2016).
Toxicity to freshwater
algae: No toxic
effects against algae were observed at the limit loading of 100 mg/L
after 72 hrs under exposure conditions (Spoo-Klöppel, 2016).
Toxicity to microorganisms:
After three hours the test material showed approx. 3 % respiration
inhibition of activated sludge at the highest concentration of 1000
mg/L. An EC-50 value of higher than 1000 mg/l and EC-10 value of 856.5
mg/l was determined (by probit analysis) (Spoo-Klöppel, 2016).
All toxicity studies mentioned
above are classified as acceptable and satisfy the guideline
requirements for the toxicity studies on acute toxicity to aquatic
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