Registration Dossier
Registration Dossier
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EC number: 701-242-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Negative for skin sensitisation (OECD 429)
Negative for respiratory sensitisation
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Reaction Products of C4 alcohols and C4 alkenes obtained as by-products from the manufacturing of butan-2-ol by sulfuric acid esterification and hydrolysis of butene was assessed for its skin sensitising potential in a Local Lymph Node Assay, according to OECD guideline 429. The test substance was found not to be a skin sensitiser.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No studies on respiratory sensitisation were identified.
There are no reports of respiratory sensitisation from this substance in laboratory animals or humans.
Justification for classification or non-classification
These findings do not warrant the classification of this substance as a skin or respiratory sensitizer under Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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