Tridecan-1-ol

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

other: spectrophotometric analytical method

Principles of method if other than guideline:

The water solubility determination of test item was done as per the OECD cguideline 105 by spectrophotometric analytical method as per OECD 101.

GLP compliance:

no

Type of method:

other: spectrophotometric analytical method

Key result

Water solubility:

131.86 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

Remarks on result:

other: No other detail available

Observation Table:

Sample stirring (h)	Concentration obtained		Average	Absorbance	Average	Dilution factor	Water Solubility value obtained (mg/L)	Average
24 h	R1	133.34	134.48	0.275	0.277	-	133.34	134.48
	R2	135.62		0.279			135.62
48 h	R1	126.62	125.96	0.261	0.260	-	126.62	125.96
	R2	125.29		0.258			125.29
72 h	R1	134.58	135.15	0.277	0.278	-	134.58	135.16
	R2	135.71		0.279			135.71

 

The water solubility for 24 h, 48 h and 72 h was calculated as follows: Mean water solubility value for

24 h + 48 h + 72 h run sample.

= (134.48 + 125.96 + 135.16)/3

= 131.86 mg/L

Conclusions:

The water solubility determination of test chemicals was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The solubility of test substance in water was determine to be 131.86 mg/L at 25°C.

Executive summary:

The study was conducted to determine the solubility of test chemical in ultra pure water according to OECD guideline 105. Test was conducted at 25+_2deg C in two stages, preliminary test for 24hrs followed by confirmatory test  for 24hrs, 48hrs and 72 hrs in replicates. The final water solubility value was calculated based on average of individual values obtained at 24hrs, 48hrs and 72 hrs. The difference between the average values in three vessels was not observed more than 15%. The water solubility value was determined to be 131.86 mg/L at 25+_2deg C. 

Based on the water solubility value determined by OECD 105 test guideline, it is confirmed that the substance is moderately soluble in water.

Description of key information

The water solubility determination of test chemicals was done as per the OECD guideline 105. The solubility of test substance in water was determine to be 131.86 mg/L at 25°C.

Key value for chemical safety assessment

Water solubility:

131.86 mg/L

at the temperature of:

25 °C

Additional information

The study was conducted to determine the solubility of test chemical in ultra pure water according to OECD guideline 105. Test was conducted at 25+_2deg C in two stages, preliminary test for 24hrs followed by confirmatory test  for 24hrs, 48hrs and 72 hrs in replicates. The final water solubility value was calculated based on average of individual values obtained at 24hrs, 48hrs and 72 hrs. The difference between the average values in three vessels was not observed more than 15%. The water solubility value was determined to be 131.86 mg/L at 25+_2deg C. 

Based on the water solubility value determined by OECD 105 test guideline, it is confirmed that the substance is moderately soluble in water.

Based on the data from reliable sources, water solubility value for the test chemical was determined to be 100 mg/L at 20°C, indicating that test substance is moderately soluble in water.