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EC number: 233-520-3
CAS number: 10213-78-2
Salmonella typhimurium strains TA98, TA100,
TA1535, TA1537 and TA1538 were treated with the test compound using the
Ames test at 5 dose levels, in triplicate, both with and without
metabolic activation. The dose range was determined in a prelimary
toxicity assay and was 0.2 to 500 µg/plate. Levels of 20, 100 and 500 µg
induced slight toxicity and were also used in the main test. The test
was not repeated. The solvent DMSO control plates gave counts of
revertant colonies within the normal range. All positive control
chemicals produced marked increases in the number of revertant colonies,
both with and without metabolic activation. The test compound caused no
significant increase in the number of revertant colonies for any of the
bacterial strains with or without metabolic activation. The test
compound was found to be non-mutagenic under the conditions of this test.
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