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EC number: 233-520-3
CAS number: 10213-78-2
One toxicity test with algae was performed. The test is well described and performed according OECD guideline 201 applying GLP conditions. The test is performed in natural river water i.e. applying the bulk approach and resulted in a 72 hr ErC10 of 34.5 µg/L and 72 hr ErC50 of 119 µg/L.
Cationic surfactants sorb strongly to anionic
matrixes like glassware, river water constituents and algae. Extraction
of cationic surfactants from these surfaces is possible but at the lower
end of the concentration range the extraction efficiency is in relation
to the detection limit in many cases not high enough. Especially in
algae studies where at the low end of the concentration range the number
of algae is still increasing with sometimes close to two orders of
magnitude it has been shown to be difficult to recover the test
substance. The use of the mean measured initial concentration to base
the dose response upon is under these conditions adviced by OECD
guideline 201 (point 40).
Tests with this type of substances using
realistic worst-case (with a low DOC and suspended matter content) river
water i.e. using the bulk approach as described in ECETOC technical
report 88, are environmentally more relevant because the river
water constituents stabilize the test substance in the test solution in
a similar way as it would occur in the environment. Results from bulk
approach tests are therefore ideal for risk assessment purposes. For
classification and labeling however mitigation by riverwater
constituents is not considered to be acceptable. To compensate for this
mitigation, the endpoints are corrected by dividing the values by a
factor of 10.
This factor of 10 is considered to be a
realistic worst-case value because only a factor of ±2 difference in
effect was observed in the algae tests with oleyl diethanolamine.
ErC50 (bulk) = 34.1 µg/L; ErC50 (normal) =
ErC10 (bulk) = 86.7 µg/L; ErC50 (normal) =
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