Registration Dossier
Registration Dossier
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EC number: 237-457-2 | CAS number: 13811-50-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a static acute toxicity test to fish, Zebra fish (Brachydanio rerio) were exposed for 96 hours according to OECD 203 (1992). The LC50 was determined to be greater than 100 mg/L but lower than 215 mg/L, the LOEC was determined to be 215 mg/L and the NOEC was determined to be 46.4 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
In a static acute toxicity test to fish, Zebra fish (Brachydanio rerio) were exposed for 96 hours according to OECD 203 (1992). Based on the results of a range finding study (LC50 after 96 h: between 10 and 100 mg/L) the concentrations, spaced by a factor of about 2 .2, were fixed as follows: 0, 10, 21.5, 46.4, 100, 215, 464 mg/L. At the beginning of the study, the analytically determined concentrations ranged from 86.6 to 90.5 % of the nominal values. At the end of the study, the analytically determined concentrations ranged from 93.7 to 102.6 % of the nominal values and confirmed the theoretical concentrations. Based on the nominal concentrations the LC50 was determined to be greater than 100 mg/L but lower than 215 mg/L, the LOEC was determined to be 215 mg/L and the NOEC was determined to be 46.4 mg/L.
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