Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-987-8 | CAS number: 112-58-3
Endpoint summary
Administrative data
Description of key information
In an OECD guideline 222 study, the 28-day NOEC value for adult E. fetida survival was 308.6 mg/kg dry substrate for dihexyl ether, while the NOEC for weight change was 1000 mg/kg dry substrate. The NOEC value based on reproduction was 308.6 mg/kg dry substrate.
In an OECD 208 guideline study, the NOEC was 1000 mg/kg dry soil in all species for emergence and survival for dihexyl ether. The NOEC for shoot biomass was 100 mg/kg dry soil for Cabbage, Carrot, Lettuce, Tomato and Barley. For Onion, the shoot biomass NOEC was 1000 mg/kg dry soil. The overall NOEC for the study was 100 mg/kg dry soil.
In an OECD 216 guideline study, dihexyl ether was not inhibitory to the nitrate formation rate. Statistically significant stimulatory effects were observed at the two highest concetrations of 81 and 243 mg/kg. The calculated EC10 was 3.3 mg/kg dry soil.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
