Registration Dossier
Registration Dossier
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EC number: 484-460-1 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
MPKO, the major hydrolysis product of OS1600, has low toxicity to algae.
Key value for chemical safety assessment
Additional information
One study on the freshwater alga (Pseudokirchneriella subcapitata), performed according to the OECD Guideline 201 is available. This study evaluated the toxicity of MPKO during a 72h exposure. Algae were exposed to a control medium and a medium containing 5.6, 10, 18, 32, 56, and 100 mg/L MPKO (nominal). Measured concentrations ranged from 92% to 100% of nominal and are expressed as nominal concentrations. Samples were taken at 0, 24, 48 and 72 hrs to determine cell density. Based on the results it could be concluded that the substance, MPKO, had an inhibitory effect with regard to growth of (Pseudokirchneriella subcapitata) at >=56 mg/L.
In conclusion, the EyC50 (biomass) was 50 mg/L MPKO and the ErC50 (growth rate) was 88 mg/L MPKO. The NOEC for both biomass and growth rate was 32 mg/L MPKO.
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