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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term measured data for the registered substance (Ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters) were available for fish, invertebrates and algae.

In an acute fish toxicity test according OECD 203 and GLP (NOTOX, 2000e), the 96h LC50for carp Cyprinus carpio exposed ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters was >100 mg/l in a static system. A 48 h EC50value of > 100 mg/l has been determined for the effects on mobility of Daphnia magna (OECD 202, NOTOX, 2000f) and 72 hour EC50value of > 220 mg/l and NOEC of 10 mg/l have been determined for the effects on growth rate of Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) (OECD 201, NOTOX, 2000g).

Ecotoxicity data were predominantly generated on the parent compound, which was supposed to display the principal aquatic hazard; the results of each of these studies are interpreted with reference to nominal concentrations of the test substance. However, it is likely that the test organisms were also exposed to the hydrolysis products of the substance. It can be concluded that the hydrolysis products shows also no toxicity up to the highest tested concentrations in the studies and exposure to the possible degradation products did not induce additional effects on survival. The PNECaqua can be calculated with the available data to reflect the hazard for all individual components in the reaction mass of [3-(trimethoxysilyl)propyl]urea, [3 (dimethoxyethoxysilyl)propyl]urea, [3(methoxydiethoxysilyl)propyl]urea and [3(triethoxysilyl)propyl]urea, the toxicity will be equal for this structural analogue components, all components of the parent substance reacts rapidly to produce the silanol hydrolysis product, [3-(trihydroxysilyl)propyl]urea. The other hydrolysis products are methanol and ethanol.

Methanol and ethanol are well characterised in the public domain literature and are not hazardous at the concentrations relevant to the studies; the short-term EC50 and LC50 values for these substances are in excess of 1000 mg/l (OECD, 2004a - SIDS for methanol, CAS 67-56-1; OECD, 2004b - SIDS for ethanol, CAS 64-17-5).

The influence of the test item ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters on the respiration rate of activated sludge was investigated according to OECD 209 and GLP (NOTOX, 1999g). No inhibition in respiration rate of the sludge was recorded in any of the ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters concentrations tested. Hence, the NOEC for ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters is 284 mg/l.