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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Old publication, not according to any guidelines, Insufficient description of the method.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1955
Report date:
1955
Reference Type:
secondary source
Title:
Acute Toxicity Data
Author:
Unknown.
Year:
1990
Bibliographic source:
J. American College Toxicol 1, 110 (1990); cited in RTECS and in ECB IUCLID4 2009.

Materials and methods

Principles of method if other than guideline:
Method: other: no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Melamine
EC Number:
203-615-4
EC Name:
Melamine
Cas Number:
108-78-1
Molecular formula:
C3H6N6
IUPAC Name:
1,3,5-triazine-2,4,6-triamine
Details on test material:
- Name of test material (as cited in study report): Melamine- Chemical name: 2,4,6-Triamino-1,3,5-triazine- Molecular formula (if other than submission substance): C3H6N6- Molecular weight (if other than submission substance): 126- Analytical purity: 99 % minimum- Stability under test conditions: Stable in aqueous solution and to moderate heating. Deammonation occurs when heated above melting point. (350 ° C).

Test animals

Species:
rabbit

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 1 000 mg/kg bw

Applicant's summary and conclusion