2,2'-(ethylenedioxy)diethanol

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

1975

Materials and methods

Principles of method if other than guideline:

Method: static fish test

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2,2'-(ethylenedioxy)diethanol

EC Number:

203-953-2

EC Name:

2,2'-(ethylenedioxy)diethanol

Cas Number:

112-27-6

Molecular formula:

C6H14O4

IUPAC Name:

2-[2-(2-hydroxyethoxy)ethoxy]ethan-1-ol

Test material form:

liquid

Specific details on test material used for the study:

- Name of test substance (as cited in publication): Triethylene glycol

Sampling and analysis

Analytical monitoring:

not specified

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

Lepomis macrochirus

Details on test organisms:

TEST ORGANISM
- Source: Test organisms obtained from commercial hatcheries from the New York metropolitan area
- Acclimation period: Fish were held for acclimation period of 14 days prior to testing
- Food type: Fish were fed with minced frozen shrimp
- Length at study initiation: 33 - 75 mm
- Fish were not fed 48 h prior to testing
- Fish that were in contact with unhealthy fish were treated for disease prevention immediately before acclimation

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Nominal and measured concentrations:

- Concentrations (ppm): 10000, 7800 (nominal)

Details on test conditions:

TEST SYSTEM
- Test vessels: all-glass, 30 gallon fish aquaria equipped with aeration and charcoal filters
- Dissolved oxygen readings taken daily and pH-value was noted at end of assay time period
- Mortality counts taken daily

Results and discussion

Effect concentrations

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)