Registration Dossier
Registration Dossier
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EC number: 206-996-5 | CAS number: 420-46-2
Endpoint summary
Administrative data
Description of key information
1,1,1-trifluoroethane is a gas at room temperature. In 4-hour inhalation exposures, there was no mortality or significant signs of toxicity even with exposures up to 2030000 mg/l (591000 ppm).
Key value for chemical safety assessment
Acute toxicity: via inhalation route
Endpoint conclusion
- Value:
- 2 030 000 mg/m³ air
Additional information
Rats were exposed for 4 -hours to levels upto 2030000mg/m3. There was no mortality and they were no significant signs of toxicity. The potential of 1,1,1 -trifluoroethane to sensitize the heart to adrenalin was evaluated in the dog. The no effect level was 860000 mg/m3 (250000 ppm) and the threshold for an effect (cardiac arrhythmia) was 1040000 mg/m3 (300000 ppm).
Justification for classification or non-classification
The data do not meet the requirements for classification and labeling.
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