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EC number: 212-454-9
CAS number: 818-61-1
Based on the following meetings of the
Commission Working Group on the Classification and Labelling of
Dangerous Substances 2-Hydroxyethyl acrylate was classified as N, R50.
ECBI/23/96 - Rev.1, SUMMARY RECORD,
Arona, 12 - 14 June 1996
DE, UK and BE proposed no
classification; FR proposed classification as N; R51 -53 or no
classification due to lack of data. The Group noted that the substance
was readily degradable. DE agreed to supply additional data which was
available from Dow which indicated classification as N; R50.
Conclusion: The Group provisionally
agreed to classify the substance as N; R50.
ECBI/31/96 - Rev. 1, SUMMARY
RECORD, Arona, 17-19 September 1996
The Group agreed to classify the
substance as N; R50.
The classification was based on an
acute toxicity study in Daphnia magna in which an EC50 of 0.78 mg/L
(nominal) was determined (Dow 1992).
Based on new evidence from short-term
and long-term studies conducted in Daphnia magna according to OECD TGs
and GLP regulations (REACH Task Force, 2013), re-evaluation of the
aquatic toxicity data and the resulting classification is proposed.
Based on available short term studies
on fish, aquatic invertebrates and algae 2-hydroxyethyl acrylate is no
subject for classification according to Regulation (EC) No 1272/2008
(CLP) with regard to acute aquatic toxicity. All endpoints determined
(LC50, EC50 and ErC50) were > 1 mg/L.
Based on NOEC values between 0.1 mg/L
and 1 mg/L determined in long term studies with aquatic invertebrates (Daphnia
magna) and algae (Pseudokirchnerella subcapitata) and the
fact that 2-hydroxyethyl acrylate is readily biodegradable and there is
no indication of a potential for bioaccumulation based on a log Pow of
-0.17 the test substance is classified as aquatic chronic, cat.3
according to Regulation (EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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