Registration Dossier
Registration Dossier
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EC number: 204-002-4 | CAS number: 112-75-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
According to the key study, the material was examined for mutagenic activity in two histidine-dependent auxotrophs of Salmonella typhimurium, strains TA98 and TA100, using por-plate assays. the studies, which were conducted in the presence and absence of an activating system derived from rat liver (S-9), employed a range of levels of the substance from 0.5 to 50µg per plate, selected following a preliminary toxicity test in strain TA98. The test included solvent (ethanol) controls with and without S-9 mix. It was concluded that the substance did not exhibit any mutagenic activity under the conditions of test.
Short description of key information:
Full details of these endpoints are provided in the IUCLID dossier and they are considered reliable.
Results are presented below:
It was concluded that the substance did not exhibit any mutagenic activity under the conditions of test.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
