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Ecotoxicological information

Toxicity to microorganisms

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Link to relevant study record(s)

Description of key information

A respiration inhibition test according to the draft OECD guideline 209 was conducted (Yoshioka et al. 1986) with activated sludge from a domestic Sewage Treatment Plant fed with synthetic sewage feed. The respiration rate was measured after a contact time of 3 hours at 5 different  concentrations. Another test was conducted with Pseudomonas putida based on a contact time of 18h. Whereas for the first test an EC50 values was derived an EC10 value was given for the second study (Huels AG, 1996)

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L
EC10 or NOEC for microorganisms:
435 mg/L

Additional information

EC50 activated sludge: 100 mg/L.

EC10 Pseudomonas putida: 435 mg/L (mean value)

Both studies were assessed as "reliable with restrictions".