Registration Dossier
Registration Dossier
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EC number: 607-759-2 | CAS number: 25618-55-7
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
Key value for chemical safety assessment
Additional information
According to Regulation (EC) No. 1907/2006, Annex IX, Column 2, 9.1.6, long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicate the need to investigate further the effects on aquatic organisms. 1,2,3 -Propanetriol, homopolymer (CAS 25618-55-7) is a readily biodegradable and soluble substance (> 550 g/L). Due to these characteristics, extensive biodegradation within conventional STPs can be expected and therefore, only low concentrations are likely to be released into the water phase and directly bioavailable to fish species. Furthermore, the acute fish tests showed no toxic effects of the substance after 96 h. The other acute studies available for aquatic invertebrates and algae (performed on analogue substance, according to Regulation (EC) No. 1907/2006, Annex XI, 1.5) also showed no toxicity. Due to the very low log Kow of - 2 bioaccumulation is not to be expected.
Based on the results of the acute tests, fish species are not expected to show a higher sensitivity compared to algae, for which a chronic value is available. Therefore, long-term toxicity testing on fish is not deemed necessary for the hazard assessment of 1,2,3 -Propanetriol, homopolymer (CAS 25618-55-7).
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