Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 258-207-9 | CAS number: 52829-07-9
Specific investigations: other studies
Administrative data
Link to relevant study record(s)
Description of key information
The test substance was shown to have a potential for binding to Ca channels and to act as an antagonist at the nicotinic acetylcholine receptors in in vitro studies. Lesions to cardiomyocytes were induced when administered intraperitoneally in rats. There is evidence that the test substance does inhibit the action of acetylcholine receptor agonists, however it does itself not evoke antinicotinic effects under normal physiological conditions.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
