Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
jan2002 - February 2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: a small study carried out using a large proportion of the working population, a deficiency was that the study only considered UK workers - facilites of the study sponsors
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Materials and methods

Study type:
medical screening
Endpoint addressed:
skin sensitisation
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Clinical examination of worforce by expert dermatologist
GLP compliance:
no

Test material

Specific details on test material used for the study:
Occupation exposure to high temperature insulation wools , including polycrystaline wools

Method

Type of population:
occupational
Ethical approval:
confirmed, but no further information available
Details on study design:
Questionaire and full skin examination, clinical screeening.

Results and discussion

Any other information on results incl. tables

Table 2 . Incidental Skin Disease Findings

  

Incidental findings of skin disease amongst those not complaining of skin problems:

 

 Contact dermatitis under leather watch strap
 Viral wart right index finger
 Mild pityriasis
 Pityrosporum folliculitis in scalp body and limbs
 Keratosis pilaris on the arms and the lymphoedema of leg post DVT
 Seborrhoeic dermatitis of the face chest and scalp
 Blue naevus in the scalp/organoid naevus in the scalp
Multiple naevi

Plantar wart right heel

Two warts right hand

skin tag axillae 

 Skin tags in axillae and neck

 

Table 3 –Findings of examination ; Profile of itch when first started

SITE

Duration

Findings on examination

Arms/Face

Few days

Nil

Arms

Few days

Nil

Neck/Arms/Face

2-3 weeks

Nil

Face/Arms

2-3 Weeks

Nil

Forearms

2 months

Psoriasis

Neck/Arms/Legs

2 weeks

Acne

Applicant's summary and conclusion

Conclusions:
In the study performed on HTIW workers in UK, no evidence of skin disease, leading to any chronic changes or any skin problems requiring long term treatment, causing long term changes to the skin or fundermentally altering an employees lifestyle where found.