Registration Dossier
Registration Dossier
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EC number: 219-460-0 | CAS number: 2439-35-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on bioaccumulation potential result:
Based on a study result with the structurally related 2-dimethylaminoethyl methacrylate (CAS 2867-47-2) it can be assumed that the test substance hydrolyses to acrylic acid (CAS 79-10-7) and dimethylaminoethanol (CAS 108-01-0) in simulated saliva and simulated intestinal fluid.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
There is no available information specific to 2-dimethylaminoethyl acrylate. However, based on the fact that the structurally related compound 2-dimethylaminoethyl methacrylate (CAS 2867-47-2) hydrolyses in simulated saliva and simulated intestinal fluid to methacrylic acid and dimethylaminoethanol (Atochem, 1994), it can be assumed that 2-dimethylaminoethyl acrylate hydrolyses enzymatically to acrylic acid (CAS 79-10-7) and dimethylaminoethanol (CAS 108-01-0) in the same circumstances.
Based on the available physical and chemical information on the test substance and the results from other toxicological studies the following additional assumptions about the toxicokinetic behaviour of the test substance can be made:
The test substance is considered to have a low bioaccumulative potential based on its log Pow of 0.68 at 25°C (MITI Japan, 1993).
Discussion on bioaccumulation potential result:
There is no available information specific to 2-dimethylaminoethyl acrylate. However, based on the fact that the structurally related compound 2-dimethylaminoethyl methacrylate (CAS 2867-47-2) hydrolyses in simulated saliva and simulated intestinal fluid to methacrylic acid and dimethylaminoethanol (Atochem, 1994), it can be assumed that this substance hydrolyses to acrylic acid (CAS 79-10-7) and dimethylaminoethanol (CAS 108-01-0) in the same circumstances.
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