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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

4-Hydroxy TEMPO was tested for reproductive toxicity to Daphnia in a 21 day semistatic test according to OECD guideline 202 Part II which was in accordance to the EU draft method C.20. The NOEC was determined at 1.5 mg/L and the LOEC at 4.5 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.5 mg/L

Additional information

The chronic toxicity of 4 -Hydroxy TEMPO to invertebrates (Daphnia magna) was investigated according to EU-method C.20 and OECD guideline 202. Daphnids were exposed to the test item for 21 days under semi-static conditions. The following concentrations were tested 0.5, 1.5, 4.5, 13.5, 40 mg/L. The NOEC was determined to be 1.5 mg/L and the LOEC was determined to be 4.5 mg/L.