Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-760-9 | CAS number: 2226-96-2
Endpoint summary
Administrative data
Description of key information
Additional information
4-Hydroxy TEMPO was tested for short-term toxicity to fish in a 96 h-semistatic test according to EU-method C.1 and OECD guideline 203. A LC50 of 545 mg/L was assessed.
4-Hydroxy TEMPO was tested for acute toxicity to aquatic freshwater invertebrates in a 48 h-static test according to EU-method C.2 and OECD guideline 202. The EC50 was assessed at 54 mg/L.
4-Hydroxy TEMPO was tested for reproductive toxicity to Daphnia in a 21 day semistatic test according to OECD guideline 202 Part II which was in accordance to the EU draft method C.20. The NOEC was determined at 1.5 mg/L and the LOEC at 4.5 mg/L.
4-Hydroxy TEMPO was tested for toxicity to algae in a 72 h-static test according to EU-method C.3 and OECD guideline 201. The EC50 based on growth rate was assessed at 1038 mg/L. The overall NOEC was determined at 22 mg/L.
4-Hydroxy TEMPO was tested for toxicity to microorganisms in a 16 hours toxicity to Pseudomonas putida test according to DIN 38412. An EC50 of 890 mg/L and an EC10 of 430 mg/L was assessed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
