Registration Dossier
Registration Dossier
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EC number: 218-218-1 | CAS number: 2082-81-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No mortality/immobilisation of adult daphnia within the first 48 h up to the highest concentration tested (30.8 mg/L) in 21d daphnia reproduction study. In a weight of evidence approach
EC50 48 h daphnia magna of 1,4-Butanediol dimethacrylate predicted by QSAR from category trend analysis of 10 methacrylates is 28.4 mg/l.
EC50 48 h daphnia magna of 1,4-Butanediol dimethacrylate predicted by QSAR from category trend analysis of 10 methacrylates is 28.4 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 28.4 mg/L
Additional information
No dedicated study on short-term toxicity of 1,4-BDDMA is available. In accordance with REACH regulation Annex VII, 9.1.1., column 1, long-term toxicity data are provided instead.
Up to the highest concentration tested (30.8 mg/L) there was no mortality of the adult daphnia within the first 48 h of the daphnia reproduction study according to OECD 211 (Noack, 2012). In conclusion, the 48h EC50 for mortality was greater than 30.8 mg/L.
EC50 48 h daphnia magna of 1,4-Butanediol dimethacrylate predicted by QSAR from category trend analysis of 10 methacrylates is 28.4 mg/l. This value corresponds with the observation the the chronic test OECD 211) with 1,4 -BDDMA.
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