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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

NOECreproduction = 3 mg/L (WAF, loading rate)

Key value for chemical safety assessment

Additional information

A chronic study investigated the effects on survival and reproductive performance in Daphnia magna during 21 days of exposure according to OECD guideline no. 211 (1998) in a semistatic study with media renewal every 48 hours. Due to the low water solubility and the impurity profile of the substance water accomodated fractions were prepared. Daphnia were exposed to water accommodated fractions at 100, 30, 10, 3, 1, 0.3 mg/l loading after separation of undissolved substance by centrifugation. Due to the high adsorption tendency test vessels were silanised. Based on the analytical results it can not be excluded that undissolved particles were present in the test solutions.

Since the impurities might have a higher solubility level than the main component, the composition of the test product in the water phase could differ markedly from the original composition of the test product when solutions were prepared at levels above the solubility limit. The concentrations of the impurities in the test solutions were not analysed in the test solutions. Given the observed effects and the number of impurities, the WAF approach was appropriate for this Daphnia study and effect concentrations could be based the loading rates.

The overall NOEC after 21 days is 3 mg/l loading.