Registration Dossier
Registration Dossier
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EC number: 221-573-5 | CAS number: 3147-75-9
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects have been observed in a chronic study with Eisenia fetida.
Key value for chemical safety assessment
Additional information
According to regulation (EC) No 1907/2006, Annex XI, paragraph 1.5., substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or "category" of substances. Environmental effects or environmental fate may be predicted from data for reference substance(s) within the group by interpolation to other substances in the group (read-across approach). For the detailed read across justification please refer to the endpoint.
To assess the toxic potential of the test item a chronic toxicity study towards Eisenia fetida according to OECD guideline 222 was conducted with a structural analogue (EC 274-570-6). The earthworms were exposed to the test item at 62.5, 125, 250, 500 and 1000 mg test item/kg soil dw for 56 d. No toxic effects on mortality, biomass and reproduction could be observed. The NOEC was determined to be >= 1000 mg/kg soil dw and the LOEC was determined to be > 1000 mg/kg soil dw.
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