Registration Dossier
Registration Dossier
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EC number: 220-713-2 | CAS number: 2873-97-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
An oral and an inhalation absorption is predicted from the phys.-chem. properties. An oral absorption was observed in the acute oral toxicity studies.
The dermal absorption is predicted to be lower.
A distribution was detected in the acute oral toxicity studies.
Diacetone acrylamide can be metabolised in vitro by hepatic microsomal enzymes and by a glutathione conjugation reaction to not identified molecules.
No accumulation is expected, based on the low log Pow.
No relevant data are available, which provide evidence on the route of excretion.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
