Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects against fish were observed at the limit of water of solubility under exposure conditions.
Key value for chemical safety assessment
Additional information
A study was performed to assess the acute toxicity of DYNS2246 to Danio rerio under semi-static conditions. The study was conducted in accordance with Council Regulation (EC) No 440/2008, Method C.1 'Acute toxicity for Fish' (2008) which is in most parts equivalent to the OECD Guideline for Testing of Chemicals No. 203 'Fish, Acute Toxicity Test' (1992). A group of seven fish of the recommended size was exposed to a limit test concentration of nominally 1 mg/L of DYNS2246 dissolved in water. Auxiliaries used to prepare the test media were an ultrasonic bath, a magnetic stirrer and folded filters. Observations were made on the number of dead fish and the incidence of sub-lethal effects after 2, 24, 48, 72 and 96 hours of exposure. The following values were determined:
LC 50 [mg/L]
2 h > 0.124
24 h > 0.107
48 h > 0.138
72 h > 0.135
96 h > 0.136
No toxic effects against fish were observed at the limit of water of solubility under exposure conditions. All results are expressed in terms of geometric mean measured concentrations.
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