Registration Dossier
Registration Dossier
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EC number: 204-004-5 | CAS number: 112-76-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: Read across: Palmitoyl chloride: With high probability acutely not harmful to fish. No toxic effects within range of water solubility.
Hydrolysis product: Stearic acid: With high probability acutely not harmful to fish. No toxic effects within range of water solubility.
Hydrolysis product: HCl: Acutely toxic for fish (pH-dependent).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 115 mg/L
Additional information
No data on the toxicity of stearoyl chloride is available. There is a fish study available for palmitoyl chloride (BASF AG, 1998).
Palmitoyl chloride hydrolyses rapidly in water therefore fish are mainly exposed to its hydrolysis product, palmitic acid.
Test concentrations were clearly above the solubility limit of palmitoyl chloride and palmitic acid as unsoluble test material was visible and the test solutions were cloudy. Test concentrations were analytically verified. No toxic effects within the range of water solubility were observed. The LC50 was determined to be ca. 115 mg/L (BASF, 1998).
A semi-static test was performed with sodium stearate (CAS 822 -16 -2; Onitsuka et al., 1989). The LC50 was determined to be 125 mg/L.
A limit test was performed with the hydrolysis product stearic acid (Leach, 1977). No toxic effect was observed at the tested concentration of 12 mg/L, which is clearly above the limit of water solubility.
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 203 with Cyprinus carpio. The 96 -h LC50 was 4.92 mg/L (acid equivalent to pH 4.3; OECD 2002).
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