Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Neither the test substance group animals nor the controls exhibited dermal reactions following challenges with 25% test substance formulation.

Therefore, under the conditions of the test AD-Cyanhydrin showed to be no skin sensitizer.


Migrated from Short description of key information:
Skin Sensitisation, Maximization Test according to Magnusson and Kligman (Guinea pig, GLP, comparable to OECD TG 406): not sensitizing
[Schering AG, Report No. 6628, 1985-06-26]

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.