Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-171-4 | CAS number: 117-08-8
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable well documented publication
Data source
Reference
- Reference Type:
- publication
- Title:
- An in vitro method for predicting sensitizing properties of inhaled chemnicals.
- Author:
- Wass U, Belin L
- Year:
- 1 990
- Bibliographic source:
- Scand J Work Environ Health 16: 208-214
Materials and methods
- Principles of method if other than guideline:
- A method for monitoring chemical reactivity in aqueous solutions as a screening model for respiratory sensitizing chemicals was developed. The chemical was allowed to react with a lysine-containing peptide, and the reaction was monitored with high-performance liquid chromatography. The results were expressed on a scale with values of 1 to 10.
- GLP compliance:
- no
- Type of method:
- in vitro
- Endpoint addressed:
- respiratory sensitisation
Test material
- Reference substance name:
- Tetrachlorophthalic anhydride
- EC Number:
- 204-171-4
- EC Name:
- Tetrachlorophthalic anhydride
- Cas Number:
- 117-08-8
- Molecular formula:
- C8Cl4O3
- IUPAC Name:
- tetrachloro-1,3-dihydro-2-benzofuran-1,3-dione
- Details on test material:
- - Name of test material (as cited in study report): Tetrachlorophthalic anhydride
Constituent 1
Results and discussion
Any other information on results incl. tables
Tetrachlorophthalic anhydride showed a reaction of 7 which is typical for a respiratory sensitizer.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
