Isopropenyl methyl ether

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted following OECD and GLP guidelines

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Report date:

2001

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Isopropenyl methyl ether

EC Number:

204-125-3

EC Name:

Isopropenyl methyl ether

Cas Number:

116-11-0

Molecular formula:

C4H8O

IUPAC Name:

2-methoxyprop-1-ene

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

ca. 118 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Effect concentrations 2

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

ca. 45 mg/L

Nominal / measured:

meas. (initial)

Conc. based on:

test mat.

Basis for effect:

growth rate

Any other information on results incl. tables

-

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The NOEC of Isopropenylmethylether for both growth inhibition and growth rate reduction corresponds with an initial concentration of 118 mg/l and a mean measured concentration of 45 mg/l based on the whole test period of 72 hours.

Executive summary:

Isopropenylmethylether did not inhibit growth of the fresh water algae species Selenastrum capricornutum at nominal loadings up to and including 200 mg/l. Based on an extra peak appearing in the chromatogramms, which increased in time, the substance was probably not hydrolytically stable. Altough the initial concentrations were significantly lower than the nominal, the initial concentrations exceed 100 mg/l at the highest nominal loading of 200 mg/l. The data further indicated a tendency to stimulation of algal growth proportional to the loading of the substance.