Registration Dossier
Registration Dossier
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EC number: 482-070-6 | CAS number: 1001354-72-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxic to the freshwater aquatic alga (72h-ErC50 Pseudokirchneriella subcapitata) was determined at 39 mg/L (nominal concentration, GLP OECD 201, static exposure), while the NOEC war determined at 0.81 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 39 mg/L
- EC10 or NOEC for freshwater algae:
- 0.81 mg/L
Additional information
Pseudokirchneriella subcapitata were exposed to six concentrations of 3- amino-4 -octanol between 0.24-100 mg/L and evaluated for effects on cell density, area under the growth curve and growth rate. Effects are estimated based on nominal test concentrations, since measurements of the test concentrations showed that Octanolamine was stable over the course of the study. Biomass was the most sensitive endpoint, however effects are reported, as indicated in the “Guidance on information requirements and chemical safety assessment: Chapter R. 7B: Endpoint specific guidance”, for the preferred observational endpoint: the growth rate at 72h. The 72-growth rate EC50 and NOEC were 39 mg/L 0.81 mg/L.
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