Registration Dossier
Registration Dossier
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EC number: 258-508-5 | CAS number: 53378-51-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-08-16 - 2012-09-13
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 D (Ready Biodegradabality: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
- GLP compliance:
- yes (incl. QA statement)
- Test organisms (species):
- sewage, domestic
- Details on inoculum:
- Secondary effluent from a municipal wastewater treatment plant in Usserød, Denmark, wihich predominantly receives domestic sewage
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- yes
- Remarks:
- benzoic acid, sodium salt
- Duration:
- 28 d
- Dose descriptor:
- other: oxygen consumption
- Effect conc.:
- 30.6 other: % of ThOD
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: oxygen elektrode
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
Remark: The test solution contains NaOH due to the production method. - Executive summary:
In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
Reference
Description of key information
OECD 301 D, 28 days, domestic sewage: oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the tested substance can be considered not inhibitory to the inoculum.
Key value for chemical safety assessment
Additional information
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