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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 March 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
20 °C
Vapour pressure:
0.017 Pa
Temp.:
25 °C
Vapour pressure:
0.034 Pa

Vapour pressure was calculated on the basis of equation log (p) = f (1/t) = a-b/(t+273.15) where p – vapour pressure in Pa, t temperature in ºC, obtained for four measurement points: 45.20 ºC, 49.20 ºC, 54.60 ºC and 60.40 ºC

 

Temperature (ºC) [t]

Vapour pressure (Pa) [P]

Evaporation rate (ug/min)

45.20

0.44

6.18

49.20

0.71

9.90

54.60

1.35

18.50

60.40

2.48

33.80

 

a= 16.1062

b = 5238.90

R2= 0.9835

Conclusions:
Vapour pressure of test item at 20ºC was 0.0172 Pa.
Vapour pressure of test item at 25 ºC was 0.0343 Pa.
Executive summary:

The vapour pressure study using effusion method was based on the method EEC A4 (based on the method OECD 104). At 20 ºC and 25ºC the determined vapour pressure was 1.72E-02 Pa and 3.43E-02 Pa respectively.

Description of key information

Key study: EEC A4 (OECD 104). Vapour pressure at 20ºC was 0.0172 Pa.

Key value for chemical safety assessment

Vapour pressure:
0.017 Pa
at the temperature of:
20 °C

Additional information

Key study: The vapour pressure study using effusion method was based on the method EEC A4 (based on the method OECD 104). At 20 ºC and 25ºC the determined vapour pressure was 1.72E-02 Pa and 3.43E-02 Pa respectively.

Supporting study: The vapour pressure of MPKO was performed was performed in accordance with OECD Guideline 104 and EU Method A.4. The vapour pressure at 20°C was 0.214 kPa.