Registration Dossier
Registration Dossier
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EC number: 411-280-2 | CAS number: 74091-64-8 MR-8A; MR-N2; NBDI
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 19.1 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 191 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 1.91 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 147 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.132 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.013 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.015 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The substance NBDI (an aliphatic diisocyanate) reacts with water. From this reaction, the diamine NBDA is formed and CO2. Available data about the conversion rate of NBDI to NBDA in water: after 3 hours a conversion rate of 60-85% was shown (depending on the initial concentration). It has been shown, in the environmental studies, that NBDA is hydrolytically stable and that the parent compound (NBDI) is not. Based on this information (e.g. half-life NBDI less than 12 hours), it is considered justified to conclude that the CSA for the environment needs to based on NBDA. All the here reported PNECs are therefore PNECs for NBDA (NBDI is not present in the environment).
Conclusion on classification
The substance is classified as hazardous to the environment (chronic env. tox. Category 3).
Note: harmonized classification, see Annex VI of Regulation No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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